The val(158)met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation

BACKGROUND: Pain is a complex experience with sensory, emotional and cognitive aspects. Genetic and environmental factors contribute to pain-related phenotypes such as chronic pain states. Genetic variations in the gene coding for catechol-O-methyltransferase (COMT) have been suggested to affect cli...

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Main Authors: Mobascher, Arian, Brinkmeyer, Juergen, Thiele, Holger, Toliat, Mohammad R, Steffens, Michael, Warbrick, Tracy, Musso, Francesco, Wittsack, Hans-Joerg, Saleh, Andreas, Schnitzler, Alfons, Winterer, Georg
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887789/
https://ncbi.nlm.nih.gov/pubmed/20509977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-32
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