Altered Markers of Tonic Inhibition in the Dorsolateral Prefrontal Cortex of Subjects With Schizophrenia

OBJECTIVE: Cognitive impairments in schizophrenia are associated with lower expression of markers of γ-aminobutyric acid (GABA) synthesis in the prefrontal cortex. The effects of GABA are mediated by GABA(A) receptors that mediate either phasic or tonic inhibition. The authors assessed the expressio...

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Main Authors: Maldonado-Avilés, Jaime G., Curley, Allison A., Hashimoto, Takanori, Morrow, A. Leslie, Ramsey, Amy J., O’Donnell, Patricio, Volk, David W., Lewis, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887737/
https://ncbi.nlm.nih.gov/pubmed/19289452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2008.08101484
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