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Multiple Rad5 activities mediate sister chromatid recombination to bypass DNA damage at stalled replication forks
DNA damage that blocks replication is bypassed in order to complete chromosome duplication and preserve cell viability and genome stability. Rad5, a PCNA polyubiquitin ligase and DNA-dependent ATPase in yeast, is orthologous to putative tumor suppressors and controls error-free damage bypass by an u...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887677/ https://ncbi.nlm.nih.gov/pubmed/20541998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.03.020 |
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