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ARB Protection Against Podocyte-Induced Sclerosis is Podocyte AT1-Independent
In the present study, we tested the hypothesis that the reno-protective effect of ARB is dependent on the angiotensin II type 1 (AT1) receptor on podocytes. For this purpose, we generated podocyte-specific knockout mice for AT1 gene (Agtr1a), and crossed with NEP25, in which selective podocyte injur...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887658/ https://ncbi.nlm.nih.gov/pubmed/20142565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.141994 |
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