The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim

BACKGROUND & AIMS: Barrett’s esophagus (BE) is a highly premalignant disease that predisposes to the development of esophageal adenocarcinoma (EAC); however, the involvement of microRNAs (miRs) in BE-EAC carcinogenic progression is not known. METHODS: Esophageal cultured cells (HEEpiC, QhTRT, Ch...

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Detalhes bibliográficos
Main Authors: Kan, Takatsugu, Sato, Fumiaki, Ito, Tetsuo, Matsumura, Nobutoshi, David, Stefan, Cheng, Yulan, Agarwal, Rachana, Paun, Bogdan C., Jin, Zhe, Olaru, Alexandru V., Selaru, Florin M., Hamilton, James P., Yang, Jian, Abraham, John M., Mori, Yuriko, Meltzer, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887605/
https://ncbi.nlm.nih.gov/pubmed/19422085
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