Treatment with respiratory syncytial virus G glycoprotein monoclonal antibody or F(ab′)(2) components mediates reduced pulmonary inflammation in mice

Therapeutic treatment with a non-neutralizing monoclonal antibody (mAb) (131-2G) specific to respiratory syncytial virus (RSV) G glycoprotein mediates virus clearance and decreases leukocyte trafficking and interferon gamma (IFN-γ) production in the lungs of RSV-infected mice. Its F(ab′)(2) componen...

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Autores principales: Miao, Congrong, Radu, Gertrud U., Caidi, Hayat, Tripp, Ralph A., Anderson, Larry J., Haynes, Lia M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for General Microbiology 2009
Materias:
Animal
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887562/
https://ncbi.nlm.nih.gov/pubmed/19264600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.009308-0
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