In vivo activity of anprocide alone, and in vitro activity in combination with conventional antibiotics against Staphylococcus aureus and Staphylococcus epidermidis biofilms

The alarming spread of multiple drug resistance in Staphylococcus aureus, combined with the frequent occurrence of S. aureus and Staphylococcus epidermidis in biofilm-type infections, indicates a growing need for new therapies. The experimental steroidal amide anprocide [3β-acetoxy-17β-(l-prolyl)ami...

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Main Authors: Pettit, Robin K., Weber, Christine A., Lawrence, Stacey B., Pettit, George R., Kean, Melissa J., Cage, Gary D.
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2009
Fag:
Antimicrobial Agents and Chemotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887550/
https://ncbi.nlm.nih.gov/pubmed/19528175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jmm.0.008268-0
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