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The N-terminal Helix Is a Post-assembly Clamp in the Bacterial Outer Membrane Protein PagP

The Escherichia coli outer membrane β-barrel enzyme PagP and its homologues are unique in that the eight-stranded barrel is tilted by about 25° with respect to the membrane normal and is preceded by a 19-residue amphipathic α-helix. To investigate the role of this helix in the folding and stability...

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Main Authors: Huysmans, Gerard H.M., Radford, Sheena E., Brockwell, David J., Baldwin, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887491/
https://ncbi.nlm.nih.gov/pubmed/17868697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.072
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