Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation

BACKGROUND: Staphylococcus aureus is a highly adaptable human pathogen and there is a constant search for effective antibiotics. Fosfomycin is a potent irreversible inhibitor of MurA, an enolpyruvyl transferase that uses phosphoenolpyruvate as substrate. The goal of this study was to identify the pa...

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Библиографические подробности
Главные авторы: Petek, Marko, Baebler, Špela, Kuzman, Drago, Rotter, Ana, Podlesek, Zdravko, Gruden, Kristina, Ravnikar, Maja, Urleb, Uroš
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Research article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887449/
https://ncbi.nlm.nih.gov/pubmed/20515462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-10-159
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