Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice

BACKGROUND: Benzo [a]pyrene (B[a]P) exposure induces DNA adducts at all stages of spermatogenesis and in testis, and removal of these lesions is less efficient in nucleotide excision repair deficient Xpc(-/- )mice than in wild type mice. In this study, we investigated by using microarray technology...

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Detalhes bibliográficos
Main Authors: Verhofstad, Nicole, Pennings, Jeroen LA, van Oostrom, Conny ThM, van Benthem, Jan, van Schooten, Frederik J, van Steeg, Harry, Godschalk, Roger WL
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887421/
https://ncbi.nlm.nih.gov/pubmed/20504355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-333
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