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Prediction of CpG-island function: CpG clustering vs. sliding-window methods

BACKGROUND: Unmethylated stretches of CpG dinucleotides (CpG islands) are an outstanding property of mammal genomes. Conventionally, these regions are detected by sliding window approaches using %G + C, CpG observed/expected ratio and length thresholds as main parameters. Recently, clustering method...

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Bibliografiske detaljer
Main Authors: Hackenberg, Michael, Barturen, Guillermo, Carpena, Pedro, Luque-Escamilla, Pedro L, Previti, Christopher, Oliver, José L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887419/
https://ncbi.nlm.nih.gov/pubmed/20500903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-327
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