Cytotoxic Xanthone Constituents of the Stem Bark of Garcinia mangostana (Mangosteen)

Bioassay-guided fractionation of a chloroform-soluble extract of Garcinia mangostana stem bark using the HT-29 human colon cancer cell line and an enzyme-based ELISA NF-κB assay, led to the isolation of a new xanthone, 11-hydroxy-3-O-methyl-1-isomangostin (1). The structure of 1 was elucidated by sp...

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Autori principali: Han, Ah-Reum, Kim, Jeong-Ah, Lantvit, Daniel D., Kardono, Leonardus B.S., Riswan, Soedarsono, Chai, Heebyung, Carcache de Blanco, Esperanza J., Farnsworth, Norman R., Swanson, Steven M., Kinghorn, A. Douglas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887388/
https://ncbi.nlm.nih.gov/pubmed/19839614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np900517h
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