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The Anopheles gambiae Oxidation Resistance 1 (OXR1) Gene Regulates Expression of Enzymes That Detoxify Reactive Oxygen Species

BACKGROUND: OXR1 is an ancient gene, present in all eukaryotes examined so far that confers protection from oxidative stress by an unknown mechanism. The most highly conserved region of the gene is the carboxyl-terminal TLDc domain, which has been shown to be sufficient to prevent oxidative damage....

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Autors principals: Jaramillo-Gutierrez, Giovanna, Molina-Cruz, Alvaro, Kumar, Sanjeev, Barillas-Mury, Carolina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887368/
https://ncbi.nlm.nih.gov/pubmed/20567517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011168
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