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Variability in the Incidence of miRNAs and Genes in Fragile Sites and the Role of Repeats and CpG Islands in the Distribution of Genetic Material

BACKGROUND: Chromosomal fragile sites are heritable specific loci especially prone to breakage. Some of them are associated with human genetic disorders and several studies have demonstrated their importance in genome instability in cancer. MicroRNAs (miRNAs) are small non-coding RNAs responsible of...

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Main Authors: Laganà, Alessandro, Russo, Francesco, Sismeiro, Catarina, Giugno, Rosalba, Pulvirenti, Alfredo, Ferro, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887363/
https://ncbi.nlm.nih.gov/pubmed/20567512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011166
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