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Variability in the Incidence of miRNAs and Genes in Fragile Sites and the Role of Repeats and CpG Islands in the Distribution of Genetic Material

BACKGROUND: Chromosomal fragile sites are heritable specific loci especially prone to breakage. Some of them are associated with human genetic disorders and several studies have demonstrated their importance in genome instability in cancer. MicroRNAs (miRNAs) are small non-coding RNAs responsible of...

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書誌詳細
主要な著者: Laganà, Alessandro, Russo, Francesco, Sismeiro, Catarina, Giugno, Rosalba, Pulvirenti, Alfredo, Ferro, Alfredo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887363/
https://ncbi.nlm.nih.gov/pubmed/20567512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011166
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