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Variability in the Incidence of miRNAs and Genes in Fragile Sites and the Role of Repeats and CpG Islands in the Distribution of Genetic Material
BACKGROUND: Chromosomal fragile sites are heritable specific loci especially prone to breakage. Some of them are associated with human genetic disorders and several studies have demonstrated their importance in genome instability in cancer. MicroRNAs (miRNAs) are small non-coding RNAs responsible of...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2010
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887363/ https://ncbi.nlm.nih.gov/pubmed/20567512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011166 |
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