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Enthalpic and entropic stages in α-helical peptide unfolding, from laser T-jump/UV Raman spectroscopy

The α-helix is a ubiquitous structural element in proteins, and a number of studies have addressed the mechanism of helix formation and melting in simple peptides. However, fundamental issues remain to be resolved, particularly the temperature (T) dependence of the rate. In this work we report appli...

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Detalhes bibliográficos
Main Authors: Balakrishnan, Gurusamy, Hu, Ying, Bender, Gretchen M., Getahun, Zelleka, DeGrado, William F., Spiro, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887291/
https://ncbi.nlm.nih.gov/pubmed/17910449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja073366l
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