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Postprandial lysophospholipid suppresses hepatic fatty acid oxidation: the molecular link between group 1B phospholipase A(2) and diet-induced obesity

Decrease in fat catabolic rate on consuming a high-fat diet contributes to diet-induced obesity. This study used group 1B phospholipase A(2) (Pla2g1b)-deficient mice, which are resistant to hyperglycemia, to test the hypothesis that Pla2g1b and its lipolytic product lysophospholipid suppress hepatic...

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Detalhes bibliográficos
Main Authors: Labonté, Eric D., Pfluger, Paul T., Cash, James G., Kuhel, David G., Roja, Juan C., Magness, Daniel P., Jandacek, Ronald J., Tschöp, Matthias H., Hui, David Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887262/
https://ncbi.nlm.nih.gov/pubmed/20215528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-144436
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