Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway

INTRODUCTION: Mechanical ventilation (MV) can injure the lungs and contribute to an overwhelming inflammatory response, leading to acute renal failure (ARF). We previously showed that poly(adenosine diphosphate-ribose) polymerase (PARP) is involved in the development of ventilator-induced lung injur...

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Hlavní autoři: Vaschetto, Rosanna, Kuiper, Jan W, Musters, René JP, Eringa, Etto C, Della Corte, Francesco, Murthy, Kanneganti, Groeneveld, AB Johan, Plötz, Frans B
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887157/
https://ncbi.nlm.nih.gov/pubmed/20346119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8932
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