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New Strategies in Head and Neck Cancer: epidermal growth factor receptor inhibition in head and neck cancer

The epidermal growth factor receptor (EGFR) is a validated target in squamous cell carcinoma of the head and neck (HNSCC). However, despite high expression of EGFR in these cancers, EGFR inhibitor monotherapy has only had modest activity. Potential mechanisms of resistance to EGFR-targeted therapies...

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Autori principali: Chen, Lucy F., Cohen, Ezra E.W., Grandis, Jennifer R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887084/
https://ncbi.nlm.nih.gov/pubmed/20406834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2318
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