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Novel genes for QTc interval. How much heritability is explained, and how much is left to find?

The corrected QT (QTc) interval is a complex quantitative trait, believed to be influenced by several genetic and environmental factors. It is a strong prognostic indicator of cardiovascular mortality in patients with and without cardiac disease. More than 700 mutations have been described in 12 gen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jamshidi, Yalda, Nolte, Ilja M, Spector, Timothy D, Snieder, Harold
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887079/
https://ncbi.nlm.nih.gov/pubmed/20519034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm156
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