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Genetic variation during lytic reovirus infection: high-passage stocks of wild-type reovirus contain temperature-sensitive mutants.

Wild-type clones of reovirus serotypes 1 (Lang), 2 (Jones), and 3 (Dearing) were serially passaged in L cells at a high multiplicity of infection, and the virus population was examined at passage levels 2, 5, and 11 for the presence of temperature-sensitive (ts) mutants. By passage 11 all three sero...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ahmed, R, Chakraborty, P R, Fields, B N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288697/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7373710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.34.1.285-287.1980
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