The Significance of p53 and K-ras Immunocytochemical Staining in the Diagnosis of Malignant Biliary Obstruction by Brush Cytology during ERCP

BACKGROUND/AIMS: Brush cytology during ERCP can provide a pathologic diagnosis in malignant biliary obstruction. K-ras and p53 mutations are commonly found in biliary and pancreatic cancers. We evaluated the diagnostic yield of brush cytology and the changes obtained by adding p53 and K-ras staining...

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Autori principali: Kim, Young Sup, Kim, Ho Gak, Han, Jimin, Hur, Change Jae, Kim, Byeong Suk, Jung, Jin Tae, Kwon, Joong Goo, Kim, Eun Young, Cho, Chang-Ho, Sohn, Yoon Kyung
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Society of Pancreatobiliary Diseases 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886932/
https://ncbi.nlm.nih.gov/pubmed/20559525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl.2010.4.2.219
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