Bronchus-Associated Lymphoid Tissue (BALT) and Survival in a Vaccine Mouse Model of Tularemia

BACKGROUND: Francisella tularensis causes severe pulmonary disease, and nasal vaccination could be the ideal measure to effectively prevent it. Nevertheless, the efficacy of this type of vaccine is influenced by the lack of an effective mucosal adjuvant. METHODOLOGY/PRINCIPAL FINDINGS: Mice were imm...

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Autors principals: Chiavolini, Damiana, Rangel-Moreno, Javier, Berg, Gretchen, Christian, Kate, Oliveira-Nascimento, Laura, Weir, Susan, Alroy, Joseph, Randall, Troy D., Wetzler, Lee M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886834/
https://ncbi.nlm.nih.gov/pubmed/20585390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011156
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