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Decrease in dietary K intake stimulates the generation of superoxide anions in the kidney and inhibits K secretory channels in the CCD

We previously demonstrated that K depletion inhibited ROMK-like small-conductance K channels (SK) in the cortical collecting duct (CCD) and that the effect was mediated by superoxide anions that stimulated Src family protein tyrosine kinase (PTK) and mitogen-activated protein kinase (MAPK) (51). How...

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Detalhes bibliográficos
Main Authors: Wang, Zhi-Jian, Sun, Peng, Xing, WenMing, Pan, ChunYang, Lin, Dao-Hong, Wang, Wen-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886822/
https://ncbi.nlm.nih.gov/pubmed/20357031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00502.2009
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