Effect of paricalcitol and cinacalcet on serum phosphate, FGF-23, and bone in rats with chronic kidney disease

Calcimimetics activate the calcium-sensing receptor (CaR) and reduce parathyroid hormone (PTH) by increasing the sensitivity of the parathyroid CaR to ambient calcium. The calcimimetic, cinacalcet, is effective in treating secondary hyperparathyroidism in dialysis patients [chronic kidney disease (C...

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Main Authors: Finch, Jane L., Tokumoto, Masanori, Nakamura, Hironori, Yao, Wei, Shahnazari, Mohammad, Lane, Nancy, Slatopolsky, Eduardo
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Editorial Focus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886812/
https://ncbi.nlm.nih.gov/pubmed/20200094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00552.2009
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