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Interleukin-2 receptor downstream events in regulatory T cells: Implications for the choice of immunosuppressive drug therapy

Naturally occurring CD4(+)CD25(high)FOXP3(+) regulatory T cells (Tregs) constitute a powerful mechanism of immune regulation and therefore, have important therapeutic potential for disorders such as autoimmune diseases, allograft rejection and graft-versus-host disease. Disruption of the IL-2R signa...

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Библиографические подробности
Главные авторы: Zeiser, Robert, Negrin, Robert S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886808/
https://ncbi.nlm.nih.gov/pubmed/18235249
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