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Interleukin-2 receptor downstream events in regulatory T cells: Implications for the choice of immunosuppressive drug therapy
Naturally occurring CD4(+)CD25(high)FOXP3(+) regulatory T cells (Tregs) constitute a powerful mechanism of immune regulation and therefore, have important therapeutic potential for disorders such as autoimmune diseases, allograft rejection and graft-versus-host disease. Disruption of the IL-2R signa...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2007
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886808/ https://ncbi.nlm.nih.gov/pubmed/18235249 |
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