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Effect of tunicamycin on herpes simplex virus glycoproteins and infectious virus production.

The antibiotic tunicamycin, which blocks the synthesis of glycoproteins, inhibited the production of infectious herpes simplex virus. In the presence of this drug, [14C]glucosamine and [3H]mannose incorporation was reduced in infected cells, whereas total protein synthesis was not affected. Gel elec...

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Bibliographic Details
Main Authors: Pizer, L I, Cohen, G H, Eisenberg, R J
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC288680/
https://ncbi.nlm.nih.gov/pubmed/6246250
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