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Food demand and meal size in mice with single or combined disruption of melanocortin type 3 and 4 receptors
Mice with homozygous genetic disruption of the melanocortin-4 receptor gene (MC4R−/−) are known to be hyperphagic and become obese, while those with disruption of the melanocortin-3 receptor gene (MC3R−/−) do not become markedly obese. The contribution of MC3R signaling in energy homeostasis remains...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886701/ https://ncbi.nlm.nih.gov/pubmed/20375267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00562.2009 |
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