Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice

Liver kinase B1 (LKB1) is a tumor-suppressing protein that is involved in the regulation of muscle metabolism and growth by phosphorylating and activating AMP-activated protein kinase (AMPK) family members. Here we report the development of a myopathic phenotype in skeletal and cardiac muscle-specif...

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Hauptverfasser: Thomson, David M., Hancock, Chad R., Evanson, Bradley G., Kenney, Steven G., Malan, Brandon B., Mongillo, Anthony D., Brown, Jacob D., Hepworth, Squire, Fillmore, Natasha, Parcell, Allen C., Kooyman, David L., Winder, William W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886679/
https://ncbi.nlm.nih.gov/pubmed/20360428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01293.2009
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