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Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure

We have generated transgenic mice that express angiotensin II (ANG II) fused downstream of enhanced cyan fluorescent protein, expression of which is regulated by the mouse metallothionein promoter. The fusion protein, which lacks a secretory signal, is retained intracellularly. In the present study,...

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Detalhes bibliográficos
Main Authors: Redding, K. M., Chen, B. L., Singh, A., Re, R. N., Navar, L. G., Seth, D. M., Sigmund, C. D., Tang, W. W., Cook, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886647/
https://ncbi.nlm.nih.gov/pubmed/20363893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00027.2010
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