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A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo
Terminally differentiated cells in Drosophila melanogaster wings and eyes are largely resistant to proliferation upon deregulation of either E2F or cyclin E (CycE), but exogenous expression of both factors together can bypass cell cycle exit. In this study, we show this is the result of cooperation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886355/ https://ncbi.nlm.nih.gov/pubmed/20548101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200910006 |
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