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Vertebrate kinetochore protein architecture: protein copy number

To define the molecular architecture of the kinetochore in vertebrate cells, we measured the copy number of eight kinetochore proteins that link kinetochore microtubules (MTs [kMTs]) to centromeric DNA. We used a fluorescence ratio method and chicken DT40 cell lines in which endogenous loci encoding...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnston, Katherine, Joglekar, Ajit, Hori, Tetsuya, Suzuki, Aussie, Fukagawa, Tatsuo, Salmon, E.D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886349/
https://ncbi.nlm.nih.gov/pubmed/20548100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912022
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