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Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

Rapid plasma membrane resealing is essential for cellular survival. Earlier studies showed that plasma membrane repair requires Ca(2+)-dependent exocytosis of lysosomes and a rapid form of endocytosis that removes membrane lesions. However, the functional relationship between lysosomal exocytosis an...

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Detalhes bibliográficos
Main Authors: Tam, Christina, Idone, Vincent, Devlin, Cecilia, Fernandes, Maria Cecilia, Flannery, Andrew, He, Xingxuan, Schuchman, Edward, Tabas, Ira, Andrews, Norma W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886342/
https://ncbi.nlm.nih.gov/pubmed/20530211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201003053
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