Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells

BACKGROUND: Wnt/β-catenin signaling is an important regulator of differentiation and morphogenesis that can also control stem cell fates. Our group has developed an efficient protocol to generate cardiomyocytes from human embryonic stem (ES) cells via induction with activin A and BMP4. METHODOLOGY/P...

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Autors principals: Paige, Sharon L., Osugi, Tomoaki, Afanasiev, Olga K., Pabon, Lil, Reinecke, Hans, Murry, Charles E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886114/
https://ncbi.nlm.nih.gov/pubmed/20559569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011134
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