Anti-α-Internexin Autoantibody from Neuropsychiatric Lupus Induce Cognitive Damage via Inhibiting Axonal Elongation and Promote Neuron Apoptosis

BACKGROUND: Neuropsychiatric systemic lupus erythematosus (NPSLE) is a major complication for lupus patients, which often leads to cognitive disturbances and memory loss and contributes to a significant patient morbidity and mortality. The presence of anti-neuronal autoantibodies (aAbs) has been ide...

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Main Authors: Lu, Xiao-ye, Chen, Xiao-xiang, Huang, Li-dong, Zhu, Chang-qing, Gu, Yue-ying, Ye, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886066/
https://ncbi.nlm.nih.gov/pubmed/20559547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011124
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