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Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

BACKGROUND: Silencing of normal gene expression occurs early in the apoptosis of neurons, well before the cell is committed to the death pathway, and has been extensively characterized in injured retinal ganglion cells. The causative mechanism of this widespread change in gene expression is unknown....

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Detalhes bibliográficos
Main Authors: Pelzel, Heather R, Schlamp, Cassandra L, Nickells, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886060/
https://ncbi.nlm.nih.gov/pubmed/20504333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-62
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