Breaking the Covalent Bond—A Pigment Property that Contributes to Desensitization in Cones

Retinal rod and cone pigments consist of an apoprotein, opsin, covalently linked to a chromophore, 11-cis retinal. Here we demonstrate that the formation of the covalent bond between opsin and 11-cis retinal is reversible in darkness in amphibian red cones, but essentially irreversible in red rods....

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Main Authors: Kefalov, Vladimir J., Estevez, Maureen E., Kono, Massahiro, Goletz, Patrice W., Crouch, Rosalie K., Cornwall, M. Carter, Yau, King-Wai
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885911/
https://ncbi.nlm.nih.gov/pubmed/15953417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.05.009
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