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A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci

Airway hyper-responsiveness (AHR) is a critical phenotype of human asthma and animal models of asthma. Other studies have measured AHR in nine mouse strains, but only six strains have been used to identify genetic loci underlying AHR. Our goals were to increase the genetic diversity of available str...

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Detalhes bibliográficos
Main Authors: Leme, Adriana S., Berndt, Annerose, Williams, Laura K., Tsaih, Shirng-Wern, Szatkiewicz, Jin P., Verdugo, Ricardo, Paigen, Beverly, Shapiro, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885868/
https://ncbi.nlm.nih.gov/pubmed/20143096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00438-010-0515-x
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