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Neighbor effects of neurons bearing protective transgenes

Viral vectors bearing protective transgenes can decrease neurotoxicity after varied necrotic insults. A neuron that dies necrotically releases glutamate, calcium and reactive oxygen species, thereby potentially damaging neighboring neurons. This raises the possibility that preventing such neuron dea...

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Detalhes bibliográficos
Main Authors: Lee, Angela L, Campbell, Laura B, Sapolsky, Robert M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885846/
https://ncbi.nlm.nih.gov/pubmed/20417625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.04.037
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