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Preparation of 5-Bromo-2-naphthol: The Use of a Sulfonic Acid as a Protecting and Activating Group

The preparation of 5-bromo-2-naphthol (4) in three steps from 5-amino-2-naphthol (1) is described. A sulfonic acid group is introduced at the 1-position as an activating and protecting group for the Sandmeyer reaction. The sulfonate group allows for the use of only water and sulfuric acid as solvent...

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Hlavní autoři: Everett, Renata, Hamilton, Jillian, Abelt, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885740/
https://ncbi.nlm.nih.gov/pubmed/20556222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/M602
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