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IgG Endopeptidase SeMac does not Inhibit Opsonophagocytosis of Streptococcus equi Subspecies equi by Horse Polymorphonuclear Leukocytes

The secreted Mac protein made by group A Streptococcus (GAS) inhibits opsonophagocytosis of GAS by human polymorphonuclear leukocytes (PMNs). This protein also has the endopeptidase activity against human immunoglobulin G (IgG), and the Cys94, His262 and Asp284 are critical for the enzymatic activit...

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Detalhes bibliográficos
Main Authors: Liu, Mengyao, Lei, Benfang
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885601/
https://ncbi.nlm.nih.gov/pubmed/20556207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874285801004010020
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