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Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase
High-throughput screening (HTS) of ~50,000 chemical compounds against phosphorylated and unphosphorylated c-Met, a tyrosine kinase receptor for hepatocyte growth factor (HGF), was carried out in order to compare hit rates, hit potencies and also to explore scaffolds that might serve as potential lea...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Open
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885599/ https://ncbi.nlm.nih.gov/pubmed/20556206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397301004010027 |
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