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With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging

TOR (target of rapamycin) is an evolutionarily conserved nutrient sensing protein kinase that regulates growth and metabolism in all eukaryotic cells. Studies in flies, worms, yeast and mice support the notion that the TOR signaling network plays a pivotal role in modulating aging. TOR is emerging a...

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Detalhes bibliográficos
Main Authors: Kapahi, Pankaj, Chen, Di, Rogers, Aric N., Katewa, Subhash D., Li, Patrick Wai-Lun, Thomas, Emma L., Kockel, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885591/
https://ncbi.nlm.nih.gov/pubmed/20519118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.05.001
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