Inflammation Causes Mood Changes Through Alterations in Subgenual Cingulate Activity and Mesolimbic Connectivity

BACKGROUND: Inflammatory cytokines are implicated in the pathophysiology of depression. In rodents, systemically administered inflammatory cytokines induce depression-like behavior. Similarly in humans, therapeutic interferon-α induces clinical depression in a third of patients. Conversely, patients...

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Main Authors: Harrison, Neil A., Brydon, Lena, Walker, Cicely, Gray, Marcus A., Steptoe, Andrew, Critchley, Hugo D.
格式: Artigo
語言:Inglês
出版: Elsevier 2009
主題:
Archival Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885494/
https://ncbi.nlm.nih.gov/pubmed/19423079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.03.015
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