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Acute Hypoxia Decreases E. coli LPS-Induced Cytokine Production and NF-κB Activation in Alveolar Macrophages

Reductions in alveolar oxygenation during lung hypoxia/reoxygenation (H/R) injury are common after gram-negative endotoxemia. However, the effects of H/R on endotoxin-stimulated cytokine production by alveolar macrophages are unclear and may depend upon thresholds for hypoxic oxyradical generation i...

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Detalhes bibliográficos
Main Authors: Matuschak, George M., Nayak, Ravi, Doyle, Timothy M., Lechner, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885487/
https://ncbi.nlm.nih.gov/pubmed/20470909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2010.05.006
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