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Phosphodiesterase 8A (PDE8A) Regulates Excitation-Contraction Coupling in Ventricular Myocytes
In ventricular myocytes, activation of protein kinase A (PKA) by 3′-5′cyclic adenosine-monophosphate (cAMP) increases the force of contraction by increasing L-type Ca(2+) channel currents (I(Ca)) and sarcoplasmic reticulum (SR) Ca(2+) release during excitation-contraction coupling. Cyclic-nucleotide...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885478/ https://ncbi.nlm.nih.gov/pubmed/20353794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.03.016 |
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