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Changes in three of the four coat proteins of oral polio vaccine strain derived from type 1 poliovirus.

Little is yet known about the nature, or extent, of the changes involved in attenuation of neurovirulent poliovirus. The tryptic comparison reported here, of coat proteins from the Sabin type 1 polio vaccine and parental Mahoney virus, provides a useful approach and affords some insight into this qu...

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Detalhes bibliográficos
Main Authors: Kew, O M, Pallansch, M A, Omilianowski, D R, Rueckert, R R
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC288542/
https://ncbi.nlm.nih.gov/pubmed/6245231
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