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DNA Cytosine Methylation in the Bovine Leukemia Virus Promoter Is Associated with Latency in a Lymphoma-derived B-cell Line: POTENTIAL INVOLVEMENT OF DIRECT INHIBITION OF cAMP-RESPONSIVE ELEMENT (CRE)-BINDING PROTEIN/CRE MODULATOR/ACTIVATION TRANSCRIPTION FACTOR BINDING

Bovine leukemia virus (BLV) proviral latency represents a viral strategy to escape the host immune system and allow tumor development. Besides the previously demonstrated role of histone deacetylation in the epigenetic repression of BLV expression, we showed here that BLV promoter activity was induc...

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Autors principals: Pierard, Valérie, Guiguen, Allan, Colin, Laurence, Wijmeersch, Gaëlle, Vanhulle, Caroline, Van Driessche, Benoît, Dekoninck, Ann, Blazkova, Jana, Cardona, Christelle, Merimi, Makram, Vierendeel, Valérie, Calomme, Claire, Nguyên, Thi Liên-Anh, Nuttinck, Michèle, Twizere, Jean-Claude, Kettmann, Richard, Portetelle, Daniel, Burny, Arsène, Hirsch, Ivan, Rohr, Olivier, Van Lint, Carine
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885223/
https://ncbi.nlm.nih.gov/pubmed/20413592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107607
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