Substitution of the myristoylation signal of human immunodeficiency virus type 1 Pr55(Gag) with the phospholipase C-δ1 pleckstrin homology domain results in infectious pseudovirion production

The matrix domain (MA) of human immunodeficiency virus type 1 Pr55(Gag) is covalently modified with a myristoyl group that mediates efficient viral production. However, the role of myristoylation, particularly in the viral entry process, remains uninvestigated. This study replaced the myristoylation...

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Detalhes bibliográficos
Main Authors: Urano, Emiko, Aoki, Toru, Futahashi, Yuko, Murakami, Tsutomu, Morikawa, Yuko, Yamamoto, Naoki, Komano, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2008
Assuntos:
Animal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885030/
https://ncbi.nlm.nih.gov/pubmed/19008404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/004820-0
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